Dr. Eben Alexander

Dr. Eben Alexander, scientist, highly trained - Harvard Medical School, Duke University School of Medicine - academic and second-generation neurosurgeon for more than 25-years

Curriculum Vitae

Birth: Charlotte, North Carolina, December, 1953

Education:

1972 Phillips Exeter Academy, Exeter, NH
1975 A.B. University of North Carolina at Chapel Hill
1980 M.D. Duke University School of Medicine, Durham, NC

Postdoctoral Training

Internship and Residencies:

1980-1981 Intern in General Surgery, Duke University Medical Center, Durham, North Carolina
1981-1983 Resident in Neurological Surgery, Duke University Medical Center, Durham, North Carolina
1985 Acting Resident in Neurology, Massachusetts General Hospital, Boston, Massachusetts
1985-1987 Resident in Neurological Surgery, Duke University Medical Center, Durham, North Carolina
1987 Senior Registrar and Cerebrovascular Fellow, Neurosurgical Service, Newcastle General Hospital, Newcastle-Upon-Tyne, England, U.K.
1988-1990 Instructor in Surgery, Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts

Research Fellowships:

1983-1985 Research Fellow in Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
1987 Research Fellow in Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts

Certifications:

1991 Diplomate, American Board of Neurological Surgery, November, 1991
1996 Inducted as a Fellow, American College of Surgeons (F.A.C.S.)

Academic Appointments:

1978-1979 Research Assistant, Neuroendocrinology, Duke University Medical Center, Durham, North Carolina
1988-1990 Instructor in Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts
1990-1994 Assistant Professor in Surgery (Neurosurgery), Harvard Medical School, Boston, Massachusetts
1990-2001 Assistant Professor in Radiation Therapy, Joint Center for Radiation Therapy, Harvard Medical School, Boston, Massachusetts
1994-2001 Associate Professor in Surgery (Neurosurgery), Harvard Medical School, Boston, Massachusetts
2001-2003 Associate Professor in Surgery (Neurosurgery), UMass Medical School, Worcester, Massachusetts
2004-2006 Consultant, Gerson Lehman, New York, NY
2008-2010 Clinical Director of the Brain Program, Focused Ultrasound Surgery Foundation, Charlottesville, Virginia
2008-present Assistant Professor of Research in Neurological Surgery, University of Virginia Medical School, Charlottesville, Virginia

Hospital Appointments:

1988-2003 Associate Surgeon, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts
1988-2003 Associate Surgeon, The Children's Hospital, Harvard Medical School, Boston, Massachusetts
1988-2003 Associate Surgeon, Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts
1994-2001 Director of Stereotactic and Functional Neurosurgery, Brigham & Women's Hospital Boston, Massachusetts
1998-2003 Clinical Associate in Neurosurgery, Massachusetts General Hospital Boston, Massachusetts
2001-2003 Active Staff, Department of Surgery, Division of Neurosurgery, University of Massachusetts Medical Center, Worcester, Massachusetts
2004-2005 Sabbatical
2005-2006 Corporate Consulting: Gerson Lehrman Group, New York, NY
2006-2007 Active Staff, Department of Surgery, Division of Neurosurgery, Lynchburg General Hospital-CentraHealth, Lynchburg, Virginia

Other Professional Positions and Major Visiting Appointments:

1978 Research Assistant in Neurosurgery, University of Minnesota School of Medicine
1980 Research Assistant in Pathology, Bowman Gray School of Medicine, Wake Forest University
1989 Visiting Lecturer and Panelist, Department of Neurosurgery, University of Virginia School of Medicine International Symposium on Stereotactic Radiosurgery
1989 Invited Lecturer, Neurology/Neurosurgery Grand Rounds, Harvard-Longwood Medical Area.
1989 Invited Faculty, Stereotactic Radiosurgery, Radionics Course in Stereotactic Techniques, Congress of Neurological Surgeons Meeting, Atlanta, Georgia
1989 Invited Lecturer, Nursing Grand Rounds, Brigham and Women's Hospital
1989 Invited Faculty, Luncheon Discussion Group on Stereotactic Radiosurgery, Congress of Neurological Surgeons Meeting, Atlanta, Georgia
1990 Co-Director, Panelist, Lecturer, Moderator, Harvard Medical School Continuing Education Course, Radiosurgery Update.
1990 Invited Lecturer and Consultant, Varian Corporation, Palo Alto, CA
1990 Invited Lecturer and panelist, Massachusetts General Hospital, Harvard Medical School, "Neurosurgery Update",post-graduate course
1990 Invited Lecturer, 14th annual New York Neurosurgery Symposium
1990 Invited Lecturer, Skull base tumor Workshop, Hannover, Germany
1990 Invited Lecturer, Framingham Union Hospital Medical Grand Rounds
1991 Invited Lecturer, Neurology/Neurosurgery Grand Rounds, Harvard-Longwood Medical Area.
1991 Invited Consultant, General Electric Medical Imaging Systems, Milwaukee, Wisconsin
1991 Invited Lecturer, First International Symposium on MR-Guided Laser Interventions, Harvard Medical School.
1991 Invited Lecturer, Providence Medical Center, Portland, Oregon.
1991 International Organizing Committee, Invited Lecturer, Moderator, International Stereotactic Radiosurgery Symposium, University of Pittsburgh School of Medicine.
1991 Invited Lecturer, Panelist, 9th European Congress on Neurosurgery, Moscow, USSR.
1991 Invited Lecturer, German-Austrian Stereotactic Workshop, Finkenberg, Austria.
1991 Invited Lecturer, Medical Grand Rounds, St. Anne's Hospital, New Bedford, Massachusetts
1991 Invited Lecturer, General Scientific Session, Congress of Neurological Surgeons, Orlando, Florida.
1991 Invited Lecturer, Boston Society of Neurology and Psychiatry.
1992 Invited Lecturer, Methodist Hospital Neurosurgical Grand Rounds, Indianapolis, Indiana
1992 Invited Lecturer, Pennsylvania State Neurosurgical Society, Philadelphia, Pennsylvania
1992 Invited Lecturer, Practical Course, American Association of Neurological Surgeons, San Francisco, California
1992 Invited Lecturer, Breakfast Seminar, American Association of Neurological Surgeons, San Francisco, California
1992 Invited Consultant, General Electric Medical Imaging Systems, Milwaukee, Wisconsin 1992 Invited Lecturer, Neurology/Neurosurgery Grand Rounds, University of Massachusetts, Worcester, Massachusetts
1992 Invited Lecturer, Workshop on Stereotactic Techniques, EuropeanSociety of Stereotactic and Functional Neurosurgery, Stockholm, Sweden
1992 Invited Lecturer, Symposium on Neuro-Radio-Surgery, Vienna, Austria
1992 Invited Lecturer and Panelist, Joint Section on Tumors Session, Congress of Neurological Surgeons, Washington, D.C.
1992 Invited Lecturer, Practical Course on Radiosurgery, Congress of Neurological Surgeons, Washington, D.C.
1992 Invited Lecturer and Panelist, Radiosurgery Course, American Society of Therapeutic Radiology and Oncology, San Diego, California
1992 Invited Lecturer, Western Medical Center, Santa Ana, California
1992 Invited Lecturer, Tumors of the Central Nervous System, Harvard Medical School, Department of Continuing Education, Boston, MA.
1993 Invited Lecturer, Practical Clinic, American Association of Neurological Surgeons Annual Meeting, Boston, Massachusetts
1993 Invited Lecturer, Breakfast Seminars, American Association of Neurological Surgeons Annual Meeting, Boston, Massachusetts
1993 Invited Lecturer, Royal Australasian College of Surgeons, Adelaide, Australia
1993 Invited Lecturer, Stereotactic Radiosurgery/Brachytherapy Workshop, Adelaide, Australia
1993 Invited Lecturer, Auckland Hospital Neurosurgery, Auckland, New Zealand
1993 Invited Lecturer, International Stereotactic Radiosurgery Society, 1st Congress Meeting, Stockholm, Sweden
1993 Invited Speaker, Santorini Radiosurgery Workshop, Santorini, Greece
1993 Invited Consultant, General Electric Medical Imaging Systems, Milwaukee, Wisconsin
1993 Invited Lecturer, UCLA Stereotactic Neurosurgery/Radiosurgery Course, Los Angeles, California
1993 Invited Lecturer, Practical Course, Congress of Neurological Surgeons, Vancouver, British Columbia, Canada
1993 Invited Lecturer, Luncheon Discussion Group, Congress of Neurological Surgeons, Vancouver, British Columbia, Canada
1993 Panelist and Moderator, XIth Meeting of the World Society for Stereotactic and Functional Neurosurgery, Ixtapa, Mexico
1993 Invited Lecturer, Tumors of the Central Nervous System, Harvard Medical School, Department of Continuing Education, Boston, MA
1993 Invited Lecturer, Intensive Review in Neurology, Harvard Medical School, Department of Continuing Education, Boston, MA
1993 Invited Lecturer, Grand Rounds, Neurology and Neurosurgery, Duke University Medical Center, Durham, NC
1994 Fischer-Leibinger Visiting Professor in Stereotactic Neurosurgery, University of Arizona, Tucson, AZ
1994 Invited Lecturer, Asia-Pacific Minimally Invasive Neurosurgery Conference, Singapore General Hospital, Singapore
1994 Visiting Professor, Ministry of Health, Government of Singapore, Tan Tock Seng Hospital, Singapore
1994 Visiting Professor, Pramongkutklao Medical School, Bangkok, Thailand
1994 Invited Lecturer, Chulalongkorn University, Bangkok, Thailand
1994 Invited Lecturer, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N.T., Hong Kong
1994 Invited Lecturer, Beijing, China
1994 Invited Lecturer, Zhong Shan Hospital, Shanghai, China
1994 Invited Lecturer, Guangxhou, China
1994 Invited Lecturer, Australian Stereotactic Workshop, Saint Vincent's Hospital, Sydney, Australia
1994 Director and Speaker, Practical Course, American Association of Neurological Surgeons, San Diego, CA
1994 Invited Speaker, Breakfast Seminars, American Association of Neurological Surgeons, San Diego, CA
1994 Invited Speaker, Harvard Longwood Oncology Group Spring Symposium, Boston, MA
1994 Invited Speaker, Interactive Neurology, Massachusetts General Hospital, Harvard Medical School Continuing Education, Boston, MA (6/23/94)
1994 Invited Lecturer, UCLA Course on Minimally Invasive Therapy of the Brain, Los Angeles, CA (8/25-27/94)
1994 Invited Lecturer and Panelist, First Brazilian Workshop of Stereotactic Radiotherapy and Radiosurgery, San Paulo, Brazil (9/1-3/94)
1994 Invited Lecturer and Panelist, XX Congresso Brasileiro de Neurocirurgia, Belo Horizonte, Brazil (9/4-8/94)
1994 Invited Speaker, Grand Rounds, The Brockton Hospital Symposium, Brockton, MA (9/16/94)
1994 Invited Speaker, The Preuss Foundation Symposium on Stereotactic Radiation Treatments for Brain Tumors, Boston, MA (9/28-30/94)
1994 Invited Lecturer, Breakfast Seminar, Congress of Neurological Surgeons, Chicago, Illinois (10/1-6)
1994 Invited Lecturer, Interventional MRI Symposium, Society for Magnetic Resonance, Boston, MA (10/8-9)
1994 Invited Lecturer, Stereotactic Neurosurgery - Hands On, American Association of Neurological Surgeons, New Orleans, LA (10/28-29)
1994 Invited Lecturer, Radiosurgery for Brain Tumors, Loyola University Medical Center, Maywood, IL (11/4-5)
1994 Invited Lecturer, Intensive Review in Neurology, Harvard Medical School, Department of Continuing Education, Boston, MA
1995 Invited Lecturer, Medical Grand Rounds, Brigham & Women's Hospital
1995 Invited Lecturer, Practical Course, American Association of Neurological Surgeons, Orlando, FL (4/22)
1995 Invited Lecturer, Tumor Section Symposium, American Association of Neurological Surgeons, Orlando, FL (4/26)
1995 Invited Speaker, Breakfast Seminars, American Association of Neurological Surgeons, Orlando, FL (4/22-27)
1995 Invited Lecturer and Panelist, 2nd Congress of the Spanish Radiosurgery Society, Madrid, Spain (4/28)
1995 Invited Special Lecturer, Panelist, 10th European Congress on Neurosurgery, Berlin, Germany (5/9).
1995 Invited Lecturer and Panelist, Virtual Reality in Medicine and Developer's Expo, Boston, MA
1995 Invited Lecturer, X-knife Consortium Meeting, Boston (6/13/95)
1995 Program Chairman, Lecturer, Moderator, International Stereotactic Radiosurgery Society 2nd Congress Meeting, Boston, MA 6/14-17/95)
1995 Invited Lecturer, Joint International Congress on Minimally Invasive Techniques in Neurosurgery and Otolaryngology, Pittsburgh, PA (6/19)
1995 Invited Panelist, Practical Course, Congress of Neurological Surgeons, San Francisco, California (10/15)
1995 Invited Lecturer, Luncheon Discussion Groups, Congress of Neurological Surgeons, San Francisco, California (10/16,18)
1995 Invited Speaker, General Electric Intraoperative MR Symposium, Congress of Neurological Surgeons, San Francisco, California (10/18)
1995 Invited Lecturer, General Scientific Plenary Session, Congress of Neurological Surgeons, San Francisco, California (10/19)
1995 Invited Panelist and Consultant, Center for Health Care, Lawrence Livermore National Laboratories, San Francisco, California (10/20)
1995 Invited Professor, Overlook Hospital, Summit, New Jersey (10/27)
1995 Invited Lecturer, New Jersey State Neurosurgical Society, New Brunswick, New Jersey (10/27
1995 Invited Lecturer, Tumors of the Central Nervous System, Harvard Medical School, Department of Continuing Education, Boston (11/14-15)
1995 Invited Lecturer, Stereotactic Neurosurgery - Hands On,American Association of Neurological Surgeons, New Orleans, LA (11/17-18)
1995 Invited Lecturer, XKnife Consortium, Orlando, FL (12/5)
1995 Invited Lecturer, LINAC Radiosurgery, 1995, University of Florida, Orlando, FL (12/6-10)
1996 Visiting Professor, Chicago Institute of Neurosurgery and Neuroresearch, Chicago, IL (12/22)
1996 Invited Lecturer and Panelist, 2nd International Skull Base Congress, VII Annual Meeting North American Skull Base Society, San Diego, CA, (6/29-7/4)
1996 Invited Lecturer and Panelist, Conference on Stereotactic Target Localization Techniques, Boston, MA, (7/20-7/21)
1996 Invited Lecturer, LINAC Stereotactic Radiosurgery/Radiotherapy Symposium, Samsung Medical Center, Seoul, Korea (9/7)
1996 Invited Lecturer, Stereotactic Radiosurgery Workshop, Tokyo University, Tokyo, Japan (9/8)
1996 Invited Lecturer, Stereotactic Radiosurgery and Radiotherapy Workshop, Queen Elizabeth Hospital, Hong Kong (9/10)
1996 Invited Lecturer, Symposium on Stereotactic Radiosurgery and Computer-Assisted Neurosurgery, Apollo Hospital, New Delhi, India (9/12)
1996 Special Guest Lecturer, Oregon Neurosurgical Society, Salishan Lodge, Oregon (10/18)
1996 Special Guest Lecturer, Oregon Neurosciences: Cost Effectiveness
1996, Salishan Lodge, Oregon (10/18)
1996 Visiting Professor, New Jersey Medical School, Newark NJ (10/22-23)
1996 Neurosurgery Grand Rounds, Hackensack Medical Center, Hackensack, NJ (10/23)
1996 Invited Lecturer, UCLA - XKnife User Group, Los Angeles, CA (10/26)
1996 Invited Lecturer, Tumors of the Central Nervous System, Harvard Medical School, Department of Continuing Education, Boston (11/26)
1996 Anesthesia Grand Rounds, Brigham & Women's Hospital, Boston, MA (11/27)
1997 Pain Service Grand Rounds, Brigham & Women's Hospital, Boston, MA (2/24)
1997 Invited Lecturer, MRI Basic to Advanced, General Electric Meeting, Breckenridge, CO (3/16)
1997 Visiting Professor, Maine Neurosurgical Society Meeting, Sugarloaf, ME (4/4-6)
1997 Invited Lecturer, Practical Course, American Association of Neurological Surgeons, Denver, CO (4/14)
1997 Invited Lecturer, General Electric Intraoperative MR Symposium, American Association of Neurological Surgeons, Denver, CO (4/16)
1997 Invited Speaker, Breakfast Seminars, American Association of Neurological Surgeons, Denver, CO (4/15,18)
1997 Invited Lecturer, Anesthesia/Critical Care Grand Rounds, Beth Israel Hospital, Boston, MA (5/21)
1997 Invited Lecturer and Moderator, International Stereotactic Radiosurgery Society 2nd Congress Meeting, Madrid, Spain (6/25-28/97)
1997 Speaker, Panelist and Moderator, XIIth Meeting of the World Society of Stereotactic and Functional Neurosurgery, Lyon, France (7/1-4/97)
1997 Invited Speaker and Moderator, 11th International Congress of Neurological Surgery, Amsterdam, The Netherlands (7/6-11/97)
1997 Visiting Professor, Tulsa Neurosciences Society, Tulsa, OK (9/11-12)
1997 Invited Panelist, Practical Course, Congress of Neurological Surgeons, New Orleans, LA (9/27-10/1)
1997 Invited Lecturer, Luncheon Discussion Groups, Congress of Neurological Surgeons, New Orleans, LA (9/27-10/1)
1997 Invited Speaker, General Electric Intraoperative MR Symposium, Congress of Neurological Surgeons, New Orleans, LA (9/27-10/1)
1997 Invited Lecturer, General Scientific Plenary Session, Congress of Neurological Surgeons, New Orleans, LA (9/27-10/1)
1997 Invited Lecturer, Brain Tumor Society, Boston, MA (11/1)
1997 Invited Lecturer, Tumors of the Central Nervous System, Harvard Medical School, Department of Continuing Education, Boston (11/25)
1998 Invited Speaker and Moderator, XKnife Radiosurgery Society Meeting, Philadelphia, PA (4/25)
1998 Invited Speaker, "Meet the Professor Session", American Society of Clinical Oncology Annual Meeting, Los Angeles, CA (5/16)
1998 Invited Speaker, General Electric Intraoperative MR Symposium, UHUHS: Uniformed Services University of the Health Sciences, Washington, DC (6/3)
1998 Invited Lecturer, Pain Management Seminar, Harvard Medical School, Department of Continuing Education, Boston (6/13)
1998 Invited Lecturer, Tumors of the Central Nervous System, Harvard Medical School, Department of Continuing Education, Boston (9/28)
1999 Invited Lecturer, "Entering the Mind Zone: A Comprehensive Neuroscience Program", Brigham & Women's Hospital Nurse Education(1/13)
1999 Invited Lecturer, West Virginia Medical Society, Charleston, WV(1/22)
1999 Invited Speaker, AANS Joint Section on Cerebrovascular Surgery, Nashville, TN (2/2)
1999 Invited Speaker and Moderator, XKnife Radiosurgery Society Meeting, Sydney, Australia (2/23)
1999 Invited Lecturer, Panelist and Moderator, International Stereotactic Radiosurgery Society 3rd Congress Meeting, Sydney, Australia (2/24-2/27)
1999 Invited Lecturer, Panelist and Moderator, 50th Anniversary of Neurosurgery in Egypt, Cairo, Egypt (3/9-3/12)
1999 Invited Lecturer, Panelist and Moderator, International Stereotactic Radiosurgery Society 3rd Congress Meeting, Sydney, Australia (2/24-2/27)
1999 Invited Lecturer, Panelist and Moderator, Japanese Society of Skull Base Surgery / Conference on Neurosurgical Techniques and Tools, Osaka, Japan (3/22-25)
1999 Invited Lecturer, Practical Course, American Association of Neurological Surgeons, New Orleans, LA (4/24)
1999 Invited Lecturer, General Electric Intraoperative MR Symposium, American Association of Neurological Surgeons, New Orleans, LA (4/26)
1999 Invited Speaker, Breakfast Seminars, American Association of Neurological Surgeons, New Orleans, LA (4/27)
1999 Invited Lecturer and Moderator, New England Neurosurgical Society, Dedham, MA (6/11)
1999 Invited Lecturer, Panelist and Moderator, American Society of Stereotactic and Functional Neurosurgery, Snowbird, UT (7/7-11)
1999 Invited Lecturer, Tumors of the Central Nervous System, Harvard Medical School, Department of Continuing Education, Boston (9/14)
1999 Visiting Professor, Stanford University Medical Center, Stanford, CA (10/1)
1999 Invited Lecturer, Neuroradiology, Head & Neck Radiology and Clinical Functional MRI and Spectroscopy, Harvard Medical School, Department of Continuing Education, Boston (10/4)
1999 Invited Panelist, Practical Course, Congress of Neurological Surgeons, Boston, MA (10/30-11/4)
1999 Invited Lecturer, Luncheon Discussion Groups, Congress of Neurological Surgeons, Boston, MA (10/30-11/4)
1999 Invited Examiner, AANS Professional Development Course: Mock Oral Board Examination, Houston, TX (11/15-16)
2000 Invited Speaker, North American Skull Base Society, Phoenix, AZ (3/17-19)
2000 Invited Speaker, Practical Course, American Association of Neurological Surgeons, San Francisco, CA (4/9)
2000 Invited Speaker, Breakfast Seminars, American Association of Neurological Surgeons, San Francisco, CA (4/11)
2000 Invited Speaker, Society of University Neurosurgeons, Boston, MA(6/14-17)
2000 Invited Panelist, Practical Course, Congress of Neurological Surgeons, San Antonio, TX (9/23-28)
2000 Invited Lecturer, Luncheon Discussion Groups, Congress of Neurological Surgeons, San Antonio, TX (9/23-28)
2000 Invited Lecturer, Tumors of the Central Nervous System, Harvard Medical School, Department of Continuing Education, Boston (12/4)
2001 Invited Lecturer and Panelist, International Stereotactic Radiosurgery Society 4th Congress Meeting, Las Vegas, Nevada (6/10-13)
2004 Medical Grand Rounds, Melrose-Wakefield Hospital, Melrose, MA (10/20)

Awards and Honors:

1977 The Engel Society
1980 Alpha Omega Alpha
1982 Brody Scholar in the History of Neuroscience
1983 American College of Surgeons Scholarship
1985 R.M.P. Donaghy Prize in Neurosurgery, Quebec and New England Neurosurgical Societies
1985 Award for Best Resident Paper, New England Neurosurgical Society
1993 Elected to "Ten Outstanding Young Leaders" (TOYL) by Greater Boston Jaycees
1995-96 Who's Who Among Outstanding Americans
1997-99 Listed in "Best Doctors in America -- Northeast Region"

Grant Support:

1996 Investigator, Brigham Surgical Group Research Grant, Rapid Rate Magnetic Cortical Stimulation for MR Cortical Mapping.
$42,000 direct costs

Memberships, Offices and Committee Assignments in Professional Societies:

1980-present American Medical Association
1980-1987 North Carolina Medical Society
1980-1987 Durham-Orange Counties Medical Society
1983-2005 Massachusetts Medical Society
1983-2001 Suffolk County Medical Society
1988 Congress of Neurological Surgeons:
1987 General Scientific Session Committee
1988 Joint Committee on Education Self-assessment and Sponsorship SANS IV Committee
1989 Luncheon Seminars Committee Poster Sessions Co-chairman Sergeant-At-Arms Committee
1989-present American Society for Stereotactic and Functional Neurosurgery (ASSFN )
1993-1995 ASSFN Board of Directors
1989-present World Society for Stereotactic and Functional Neurosurgery
1989-present Joint Section on Stereotactic and Functional Neurosurgery of the American Association of Neurological Surgeons
1991-1992 Chairman, Resources Committee, Joint Section on Tumors, American Association of Neurological Surgeons and Congress of Neurological Surgeons
1991-1993 Self-Assessment for Neurological Surgery SANS V Committee
1991-1995 Stereotactic Radiosurgery Task Force Member, American Association of Neurological Surgeons
1991-1992 Chairman, Registration Committee, Congress of Neurological Surgeons
1992-1993 Chairman, Registration Committee, American Association of Neurological Surgeons
1992-1994 Joint Committee on Self-Assessment, AANS/CNS
1983-1987 Joint Committee on Continuing Medical Education, AANS/CNS
1992-1997 Chairman, Subcommittee on Education, Joint Section on Tumors, American Association of Neurological Surgeons and Congress of Neurological Surgeons
1992-1997 Executive Council, Joint Section on Tumors, American Association of Neurological Surgeons and Congress of Neurological Surgeons
1992-1995 Editor, World Directory of Neurological Surgeons (North American Edition), Congress of Neurological Surgeons
1993-2001 Affiliate Member, American Society for Therapeutic Radiology and Oncology
1994-1996 Executive Council, Joint Section on Stereotactic and Functional Neurosurgery, American Association of Neurological Surgeons and Congress of Neurological Surgeons
1994-1995 Program Chairman, International Stereotactic Radiosurgery Society Meeting, Boston 1995
1994-1996 Chairman, Membership Committee, International Stereotactic Radiosurgery Society
1994-1998 Member, Board of Directors, American Association of Stereotactic and Functional Neurosurgery
1994 Scientific Program Committee, Congress of Neurological Surgeons, San Francisco, CA 1995
1997-1999 Chairman, Scientific Program Committee, International Stereotactic Radiosurgery Society Meeting, Sydney 1999
1997-1998 President, XKnife Radiosurgery Society

Editorial Boards:

1987-1993 Congress of Neurological Surgeons: Clinical Neurosurgery
1994-2003 Journal of Image Guided Surgery
1994-1999 Journal of Stereotactic and Functional Neurosurgery
1994-2003 Ad Hoc Reviewer, Neurosurgery
1999-2000 Methods in Biomedical Magnetic Resonance Imaging and Spectroscopy

Major Research Interests:

1) Advances in 3-dimensional imaging capabilities for enhancement of intraoperative management of intracranial tumors and vascular lesions, including image fusion between CT, MRI and SPECT, magnetic stimulation preoperative cortical mapping, and the Intraoperative MRI (MR/T) Project with the General Electric Corporation
2) Development of technical advances in the use of stereotactic radiosurgery using a modified linear accelerator and the proton beam in the treatment of neoplastic, vascular and functional lesions in the central nervous system
3) MR-guided Focused Ultrasound Surgery for the treatment of tumors (benign and malignant), clot dissolution in stroke and intracerebral hemorrhage, neuromodulation, creation of focal brain lesions, and precise targeted delivery of drugs and genes within the brain.

Principal Clinical and Hospital Service Responsibilities:

1988-2003 Attending neurosurgeon
2006-2007 Attending neurosurgeon

Teaching Experience:

1988-89 Neurobiology Course, Tutorial Leader, New Pathway, Harvard Medical School.
1988-93 Clinical Instructor, Physical Diagnosis Course, Second Year Medical Students, Harvard Medical School.
1988-93 Surgery Elective, Neurosurgery Didactic Sessions, Harvard Medical School.
1990 Invited Lecturer, Postgraduate Medical Series Neurosurgery Session, Brigham & Women's Hospital
1993 Thesis Review, Graduation with Honors Program, Harvard Medical School
1993 Invited Lecturer, Human Nervous System and Behavior, Harvard Medical School Source

Learn more about Dr. Alexander’s November 2008 discovery here.

PUBLICATIONS

Publications in Medicine

1. Soules, MR, Hughes, CL Jr., Garcia JR, Livengood, CH, Prystowsky, MR, Alexander, E III. Nausea and vomiting of pregnancy: Role of human chorionic gonadotropin and 17- hydroxyprogesterone.Obstetrics and Gynecology. 1980: 55(6): 696-700.

2. Alexander, E., Jr., Alexander E., III. German influence on the work of Harvey Cushing, the pioneer of neurosurgery in America. Neurosurgery. 1981: 9 (5) 501-505.

3. Alexander, E., III, Friedman, AH. Characteristics of adrenergic receptors in human pial arterioles. Surgical Forum. 1983: 43: 508.

4. Alexander, E, III, Black, P McL, Liszczak, TM, Zervas, NT. Delayed CSF lavage for arteriographic and morphological vasospasm after experimental SAH. J Neurosurg. 1985: 63:9 49-958.

5. Rossitch, E, Jr, Alexander, E, III, Schiff, SJ, Bullard, DE. Computer tomography guided stereotactic aspiration of a brainstem abscess. Clinical Neurology and Neurosurgery. 1988: 90:365-368.

6. Rossitch E, Jr., Carrazana, EJ, Ellenbogen, RG, Alexander, E, III. Kluver-Bucy syndrome following recovery from transtentorial herniation. British Journal of Neurosurgery. 1989: 3: 503-506.

7. Alexander E, III, Siddon, RL, Loeffler, JS. The acute onset of nausea and vomiting following stereotactic radiosurgery: Correlation with total dose to area postrema. Surgical Neurology. 1989:32: 40-44.

8. Loeffler, JS, Alexander E, III, Siddon RL, Saunders, WM, Coleman, CN, Winston, KR. Stereotactic radiosurgery for intracranial arteriovenous malformations using a standard linear accelerator. International J Radiation Oncology, Biology and Physics. 1989: 17: 673-677.

9. Alexander, E, III, Rossitch, E, Jr., Small, K, Rossenwasser, GO, Abson, P. Merkel cell carcinoma: long term survival in a patient with proven brain metastasis and presumed choroid metastasis. Clinical Neurology and Neurosurgery. 1989: 91 (4):317-320.

10. Small, KW, Rosenwasser, GO, Alexander, E III, Rossitch, E Jr, Dutton JJ. Presumed choroidal metastasis of Merkel cell carcinoma. Annals of Ophthalmology. 1990: 22:187-190.

11. Loeffler, JS, Alexander, E, III. The role of stereotactic radiosurgery in the management of intracranial tumors. Oncology. 1990: 4(3): 21-31.

12. Loeffler, JS, Kooy, HM, Wen, PY, Fine, HA, Cheng, C-W, Mannarino, EG, Tsai, JS, Alexander, E, III. The treatment of recurrent brain metastases with stereotactic radiosurgery. Journal of Clinical Oncology. 1990: 8(4): 576-582.

13. Rossitch, E Jr, Moore, MR, Alexander, E, III, Black, PMcL. The neurosurgeon's neurosurgeon. Cushing operates on a Penfield. Surgical Neurology. 1990: 33:150-153.

14. Crawford, JM, Rossitch, E, Jr., Oakes, WJ, Alexander, E, III. Arteriovenous malformation of the great vein of Galen associated with patent ductus arteriosus: Report of three cases and review of the literature. Child's Nervous System. 1990: 6:18-22.

15. Loeffler, JS, Rossitch E, Jr., Siddon, RL, Moore, MR, Rockoff, MA, Alexander, E, III. The role of stereotactic radiosurgery with a linear accelerator in the treatment of intracranial arteriovenous malformations and tumors in children. Pediatrics. 1990: 85(5): 774-782.

16. Alexander E III, Moore, MR, Siddon, RL, Rossitch E, Jr., Loeffler, JS. Successful management of intracranial arteriovenous malformations (AVM) with stereotactic external beam using a standard linear accelerator. Stereotactic and Functional Neurosurgery. 1990: 54 + 55: 548-549.

17. Alexander E III, Rossitch E, Jr., Siddon, RL, Moore, MR, Loeffler, JS. The role of stereotactic radiosurgery with a linear accelerator in the treatment of pediatric intracranial tumors. Stereotactic and Functional Neurosurgery. 1990: 54 + 55: 549-550.

18. Loeffler JS, Siddon RL, Wen PY, Nedzi LA, Alexander E III. Stereotactic radiosurgery of the brain using a standard linear accelerator: study of early and late effects. Radiotherapy and Oncology. 1990: 17:311-321.

19. Nashold, BS, Jr., Rossitch, E, Jr., Alexander, E, III. Dorsal root entry zone surgery for pain management: An update. Pain Management. 1991: 4(1): 15-23.

20. Alexander E III, Friedman, AH. Radioligand binding to adrenergic receptors in human pial membranes. Neurosurgery. 1990: 27(1):52-59.

21. Loeffler JS, Alexander E III, Hochberg FH, Wen PY, Morris J, Siddon RL, Schoene W, Morse RH, Black PMcL. Clinical patterns of failure following stereotactic interstitial irradiation in malignant gliomas. Int J Radiat Oncol Biol Phys 1990:19:1455-1462.

22. Carvalho PA, Schwartz RB, Alexander E III, Loeffler JS, Zimmermann RE, Nagel JS, Holman BL. Extracranial metastatic glioblastoma: appearance on T1-201 chloride/Tc- 99m-hmpao SPECT. J Nucl Med 1991: 32:322-324.

23. Rossitch E Jr, Alexander, E III, Black, PM, Cooke JP. L-arginine normalizes endothelial function in cerebral vessels from hypercholesterolemic rabbits. J Clin Invest. 1991: 87: 1295-1299.

24. Loeffler JS, Alexander E III, Wen PY, Shea WM, Coleman CN, Kooy HM, Fine HA, Nedzi LA, Silver B, Riese NE, Black PM. Results of stereotactic brachytherapy used in the initial management of patients with glioblastoma. J Nat Cancer Inst. 1990: 82:1918- 1921.

25. Tsai J-S, Buck BA, Svensson GK, Alexander E III, Cheng C-W, Mannarino EG, Loeffler JS. Quality assurance in stereotactic radiosurgery using a standard linear accelerator. Int J Radiat Oncol Biol Phys 21: 737-748, 1991.

26. Kooy HM, Nedzi LA, Loeffler JS, Alexander E III, Cheng CW, Mannarino E, Holupka E, Siddon RL. Treatment planning for stereotactic radiosurgery of intracranial lesions. Int J Radiat Oncol Biol Phys. 21: 683-693, 1991.

27. Nedzi LA, Kooy H, Alexander E III, Gelman RS, Loeffler JS. Variables associated with the development of complications from radiosurgery of intracranial tumors. Int J Radiat Oncol Biol Phys. 21: 591-599, 1991.

28. Holman BL, Zimmerman RE, Johnson KA, Carvalho PA, Schwartz RB, Loeffler JS, Alexander E, Pelizzari CA, Chen GTY. Computer-assisted superimposition of magnetic resonance and high resolution Technetium-99m-HMPAO and Thallium-201 SPECT images of the brain. J Nucl Med 32(8):1478-1484, 1991.

29. Loeffler JS, Macklis RM, Wen PY, Fine HA, Alexander E III, Coleman CN. Alternative and future strategies in the treatment of malignant gliomas. Semin Rad Oncol,1: 69-78, 1991.

30. Alexander, E III, Loeffler, JS: Introduction, to Radiosurgery: Enhancement of Clinical Excellence, Alexander, E III, Loeffler, JS, Gildenberg, PL, Franklin, PO (Eds). Stereotactic and Functional Neurosurgery, 1992: 57(1): 5-6.

31. Coleman CN, Noll L, Riese N, Buswell L, Howes AE, Loeffler JS, Alexander E III, Wen P, Harris JR, Kramer RA, Hurwitz SJ, Neben TY, Grigsby P. Final report of the Phase I trial of continuous infusion etanidazole (SR2508): A radiation therapy oncology group study. Int J Radiat Oncol Biol Phys. 22: 577-580, 1992.

32. Hurwitz SJ, Coleman CN, Riese N, Loeffler JS, Alexander E III, Buswell L, Neben TY, Shargel L, Kramer RA. Distribution of etanidazole into human brain tumors: Implications for treating high grade gliomas. Int J Radiat Oncol Biol Phys. 22:573-576, 1992.

33a. Schwartz RB, Carvalho PA, Alexander E III, Loeffler JS, Folkerth R, Holman BL. Dual isotope SPECT using T1-201 and Tc-99m hmpao in the differentiation of radiation necrosis from recurrent glioma. AJNR 12: 1187-1192, 1991.

33b. Schwartz RB, Carvalho PA, Alexander E III, Loeffler JS, Folkerth R, Holman, BL: Radiation necrosis versus high - grade recurrent glioma: differentiation by using dual isotope SPECT using T1-201 and Tc-99m HMPAO. AJR 158: 399-404, 1992

34. Loeffler JS, Alexander E III, Shea WM, Wen PY, Fine HA, Kooy HM, Black P McL: Radiosurgery as part of the initial management of patients with malignant gliomas. J Clinical Oncology, 10:1379-1385,1992.

35. Carvalho PA, Schwartz RB, Alexander E III, Garada BM, Zimmerman RE, Loeffler JS, Holman BL. Detection of recurrent gliomas with quantitative Thallium-201/ Technetium-99m hmpao single-photon emission computed tomography. J Neurosurg 77 (4): 565-570, 1992.

36. Alexander E III, Loeffler JS. Radiosurgery for intracranial vascular malformations: techniques, results and complications. Clin Neurosurg 39: 273-291, 1992.

37. Nedzi LA, Kooy HM, Alexander E III, Svensson GK, Loeffler JS: Dynamic field shaping for stereotactic radiosurgery: A modeling study. Int J Radiat Oncol Biol Phys 25:859-869, 1993.

38. Alexander E III, Loeffler JS, Schwartz RB, Johnson KA, Carvalho PA, Garada BM, Zimmerman RE, Holman BL. Thallium-201 Technetium-99m HMPAO stereotactic craniotomies in heavily irradiated malignant glioma patients. Acta Neurochirurgica 122: 215-217, 1993.

39. Tishler RB, Loeffler JS, Lunsford LD, Duma C, Alexander E III, Kooy HM, Flickinger JC: Tolerance of cranial nerves of the cavernous sinus to radiosurgery. Int J Radiat Oncol Biol Phys, 27: 215-221, 1993.

40. Kooy HM, Nedzi LA, Ledoux RL, Alexander E III, Loeffler JS: Dose-volume histogram computations for small intracranial volumes. Med Phys 20: 755-760, 1993.

41. Black P McL, Tarbell N, Alexander E III, Rockoff M, Zhan, M, Loeffler JS: Stereotactic techniques in managing pediatric brain tumors. Child's Nerv Syst: 9:343- 347, 1993.

42. Alexander E III: Glioblastoma Revisited: Do clinical observations match basic science theory? Radiosurgery: Clinical observations. J Neuro-oncology 17: 167-173, 1993.

43. Haregewoin A, Alexander E III, Black P McL, Loeffler JS: Autocrine regulation of the production of the gaseous messenger nitric oxide in a glioblastoma cell line. Experimental Cell Research 210:137-1139, 1994.

44a. Larson DA, Bova F, Eisert D, Kline R, Loeffler J, Lutz W, Mehta M, Palta J, Schewe K, Schultz C, Shaw E, Wilson JF, Lunsford LD, Alexander E, Chapman P, Coffey R, Friedman W, Harsh G IV, Maciunas R, Olivier A, Steinberg G, Walsh J: Consensus statement on stereotactic radiosurgery quality improvement. Int J Radiat Oncol Biol Phys 28:527-530, 1994.

44b. Lunsford LD, Alexander E, Chapman P, Coffey R, Friedman W, Harsh G IV, Maciunas R, Olivier A, Steinberg G, Walsh J, Larson DA, Bova F, Eisert D, Kline R, Loeffler J, Lutz W, Mehta M, Palta J, Schewe K, Schultz C, Shaw E, Wilson JF: Consensus statement on stereotactic radiosurgery quality improvement. Neurosurgery 34:193-195, 1994.

45. Gleason PL, Kikinis R, Altobelli D, Wells W, Alexander E III, Black PM, Jolesz F: Video registration virtual reality for nonlinkage stereotactic surgery. Stereotact Functional Neurosurgery 63 (1-4): 139-143, 1994.

46. Kooy HM, Van Herk M, Barnes PD, Alexander E III, Dunbar SF, Tarbell NJ, Mulkern RV, Holupka EJ, Loeffler JS: Image fusion for stereotactic radiotherapy and radiosurgery treatment planning. Int J Radiat Oncol Biol Phys 28:1229-1234, 1994.

47. Wen PY, Alexander E III, Black PM, Fine HA, Riese N, Levin JM, Coleman CN, Loeffler JS: Long term results of stereotactic brachytherapy used in the initial treatment of patients with glioblastomas. Cancer 73:3029-2036, 1994.

48. Riese NE, Loeffler JS, Wen PY, Alexander E III, Black P McL, Coleman CN: A phase I study of etanidazole and radiotherapy in malignant glioma. Int J Radiat Oncol Biol Phys 29:617-620, 1994.

49. Hughes-Davies L, Mannarino E, Alexander E III, Kooy H, Loeffler JS: Technical modifications required to treat cervical chemodectomas with stereotactic radiosurgery. Surg Neurol 41:418-420, 1994.

50. Dunbar SF, Tarbell NJ, Kooy HM, Alexander E III, Black P McL, Barnes PD, Goumnerova L, Scott RM, Pomeroy S, LaVally B, Sallan SE, Loeffler JS: Stereotactic radiotherapy for pediatric and adult brain tumors: preliminary report. Int J Radiat Oncol Biol Phys, 30:531-539, 1994.

51. Loeffler JS, Shrieve DC, Alexander E III: Radiosurgery for glioblastoma multiforme: the importance of selection criteria. Int J Radiat Oncol Biol Phys 30:731-733, 1994.

52. Bodis S, Alexander E III, Kooy H, Loeffler JS: The prevention of radiosurgery-induced nausea and vomiting by ondansetron: evidence of a direct effect on the central nervous system chemoreceptor trigger zone. Surg Neurol 42(3):249-252, 1994.

53. Shrieve DC, Tarbell NJ, Alexander E III, Kooy HM, Black PMcL, Dunbar S, Loeffler JS: Stereotactic radiotherapy: a technique for dose optimization and escalation for intracranial tumors. Acta Neurochir 62:55-60, 1994.

54. Alexander E III, Moriarty TM, Davis RB, Wen PY, Fine HA, Black PM, Kooy HM, Loeffler JS: Stereotactic radiosurgery for the definitive, noninvasive treatment of brain metastases. J National Cancer Institute 87 (1):34-40, 1995.

55. Alexander E III, Kooy HM, van Herk M, Schwartz M, Barnes PD, Tarbell N, Mulkern RV, Holupka EJ, Loeffler JS: MRI-Directed stereotactic neurosurgery: Use of image fusion with CT to enhance spatial accuracy. J Neurosurg 83:271-276, 1995.

56. Stokes MA, Soriano SG, Tarbell NJ, Loeffler JS, Alexander E III, Black PMcL, Rockoff MA: Anesthesia for stereotactic radiosurgery in children. J Neurosurg Anesth, 7:100-108, 1995.

57. Shrieve DC, Alexander E III, Wen PY, Fine HA, Kooy HM, Black PM, Loeffler JS: Comparison of stereotactic radiosurgery and brachytherapy in the treatment of recurrent glioblastoma multiforme. Neurosurg 36(2): 275-284, 1995.

58. Sarkaria JN, Mehta MP, Loeffler JS, Buatti JM, Chappell RJ, Levin AB, Alexander E III, Friedman WA, Kinsella TJ: Radiosurgery in the initial management of malignant gliomas: survival comparison with the RTOG recursive partitioning analysis. Int J Radiat Oncol Biol Phys 32:931-941, 1995.

59. Schwartz MS, Loeffler JS, Black P McL, Shrieve DC, Wen PY, Fine HA, Alexander E III. Reoperation following radiosurgery of glioblastoma: impact on survival and neurologic status. Radiosurgery 1:141-157, 1996.

60. Moriarty TM, Loeffler JS, Black P McL, Shrieve DC, Wen PY, Fine HA, Kooy HM, Alexander E III. Long-term follow-up of patients treated with stereotactic radiosurgery for single or multiple brain metastases. In: Alexander E III, Kondziolka D, Lindquist C, Loeffler JS, (eds), Radiosurgery 1995, Karger, Basel, pp 83-91, 1996.

61. Kooy HM, Cosman ER, Harlan RB, Ledoux RJ, Bellerive MR, Hacker FL, Killoran JH, Mannarino EG, Tarbell NJ, Alexander E III, Shrieve DC, Loeffler JS: A dynamic collimator system for conformal stereotactic radiosurgery and radiotherapy. In: Alexander E III, Kondziolka D, Lindquist C, Loeffler JS, (eds), Radiosurgery 1995, Karger, Basel, pp 276-287, 1996.

62. Loeffler JS, Shrieve DC, Alexander E III, Kooy HM, Tarbell NJ, Stieg PE, Wen PY, Black P McL: Stereotactic radiotherapy for meningiomas. In: Alexander E III, Kondziolka D, Lindquist C, Loeffler JS, (eds), Radiosurgery 1995, Karger, Basel, pp 47- 54, 1996.

63. Schulder M, Loeffler JS, Howes AE, Alexander E III, Black P McL: The radium bomb: Harvey Cushing and the interstitial irradiation of gliomas. J Neurosurg 84:530-532, 1996.

64. Kikinis R, Gleason PL, Moriarty TM, Moore MR, Alexander E III, Stieg PE, Matsumae M, Lorenson WE, Cline HE, Black PM, Jolesz FA: Computer-assisted interactive three-dimensional planning for neurosurgical procedures. Neurosurgery 38 (4): 640-651, 1996.

65. Auchter RM, Lamond JP, Alexander E III, Buatti JM, Chappell R, Friedman WA, Kinsella TJ, Levin AB, Noyes WR, Schultz CJ, Loeffler JS, Mehta MP: A multiinstitutional outcome and prognostic factor analysis of radiosurgery for resectable single brain metastasis. Int J Radiat Oncol Biol Phys 35:27-35, 1996.

66. Alexander E III, Moriarty TM, Loeffler JS: Radiosurgery for Metastases. J Neuro Oncol 27:279-285, 1996.

67. Ettinger GJ, Grimson WEl, Leventon ME, Kikinis R, Gugino V, Cote W, Karapelou M, Aglio L, Shenton M, Potts G, Alexander E: Non-invasive functional brain mapping using registered transcranial magnetic stimulation. Proceedings of IEEE Workshop on Mathematical Methods in Biomedical Image Analysis, San Francisco, CA, June 21-22, pp. 32-41, 1996.

68. Patrice SJ, Sneed PK, Flickinger JC, Shrieve DC, Pollack BE, Alexander E III, Larson DA, Kondziolka DS, Gutin PH, Wara WM, McDermott MW, Lunsford LD, Loeffler JS: Radiosurgery for hemangioblastoma: results of a multiinstitutional experience. Int J Radiat Oncol Biol Phys 35:493-499, 1996.

69. Schwartz RB, Holman BL, Garada BM, Carvalho PA, Folkerth R, Schwartz MS, Loeffler JS, Shrieve DC, Polak JF, Black PM, Alexander E III: Dual isotope single-photon emission computerized tomography used for prediction of histology and survival in patients after high-dose radiotherapy for malignant astrocytoma. Neurosurgical Focus 1(3), Article 1, 1996.

70. Varlotto JM, Shrieve DS, Alexander E III, Kooy HM, Black PMcL, Loeffler JS: Fractionated stereotactic radiotherapy for the treatment of acoustic neuromas: preliminary results. Int J Radiat Oncol Biol Phys 36:141-145, 1996.

71. Black PMcL, Alexander E III, Tarbell NJ, Shrieve DS, Goumnerova LC, Loeffler JS: Linear accelerator-based radiosurgery for malignant tumors of the central nervous system. Critical Rev in Neurosurg 6:225-231, 1996.

72. Schulder M, Black PMcL, Alexander E III, Loeffler JS: The influence of Harvey Cushing on neuroradiologic therapy. Therapeutic Radiology 201:671-674, 1996.

73. Alexander E III, Moriarty TM, Kikinis R, Jolesz FA: Innovations in minimalism: Intraoperative MRI. Clinical Neurosurgery 43: 338-352, 1996.

74. Schulder M, Black PMcL, Shrieve DC, Alexander E III, Loeffler JS: Permanent low-activity iodine-125 implants for cerebral metastases. J Neuro-Oncology 33:213-221, 1997.

75. Black PM, Moriarty T, Alexander E III, Stieg P, Woodard EJ, Gleason PL, Martin CH, Kikinis R, Schwartz RB, Jolesz FA: Development and implementation of intraoperative magnetic resonance imaging and its neurosurgical applications. Neurosurgery 41(4): 831- 842, 1997.

76. Nakajima S, Kikinis R, Black PM, Atsumi H, Leventon ME, Hata N, Metcalf DC, Moriarty TM, Alexander E III, Jolesz FA: Image-guided neurosurgery at Brigham & Women's Hospital. In: Computer-Assisted Surgery, Tamaka N, Ehara K, eds. Springer- Verlag, Tokyo, 144-162, 1997.

77. Alexander E III, Moriarty TM, Kikinis R, Black P, Jolesz FM. The present and future role of intraoperative MRI in neurosurgical procedures. Stereotact Functional Neurosurgery 68:10-17, 1997.

78. Alexander E III, Loeffler JS: Radiosurgery for primary malignant brain tumors. Semin Surg Oncol 14:43-52, 1998.

79. Hakim R, Loeffler JS, Wen PY, Fallon MP, Black PM, Stieg PE, Alexander E III. Linac radiosurgery for meningiomas. In: Alexander E III, Kondziolka D, Lindquist C, Loeffler JS, (eds), Radiosurgery 2, Karger, Basel, pp 16-24, 1998.

80. Chang EL, Loeffler JS, Riese NE, Wen PY, Alexander E III, Black PM, Coleman CN: Survival results from a phase I study of etanidazole (SR2508) and radiotherapy in patients with malignant glioma. Int J Radiat Oncol Biol Phys 40(1): 65-70, 1998.

81. Hakim R, Alexander E III, Loeffler JS, Shrieve DC, Wen PY, Fallon MP, Stieg PE, Black PM. Results of linar accelerator-based radiosurgery for intracranial meningiomas. Neurosurgery 42(3): 446-454, 1998.

82. Schwartz RB, Holman BL, Polak JF, Garada BM, Schwartz MS, Folkerth R, Carvalho PA, Loeffler JS, Shrieve DC, Black PM, Alexander E III. Dual-isotope single-photon emission computerized tomography scanning in patients with glioblastoma multiforme: association with patient survival and histopathological characteristics of tumor after high- dose radiotherapy. J Neurosurg 89:60-68, 1998.

83. Schwartz RB, Hsu L, Black PM, Alexander E III, Wong TZ, Klufas RA, Moriarty T, Martin C, Isbister HG, Cahill CD, Spaulding SA, Kanan AR, Jolesz FA. Evaluation of intracranial cysts by intraoperative MR. JMRI 8:807-813, 1998.

84. Potts GF, Gugino LD, Leventon ME, Grimson, EL, Kikinis R, Cote W, Alexander E, et al. Visual hemifield mapping using transcranial magnetic stimulation coregistered with cortical surfaces derivwed from magnetic resonance images. J Clin Neurophysiol 15(4):344-350, 1998.

85. Schwartz RB, Hsu L, Kacher DF, Wong TZ, Alexander E III, Okon S, Guttmann CRG, Black PM, Kelley RA, Moriarty T, Martin C, Isbister HG, Cahill CD, Spaulding SA, Jolesz FA. Intraoperative dynamic MRI: Localization of sites of brain tumor recurrence after high-dose radiotherapy. JMRI 8:1085-1089, 1998.

86. Mitsumori M, Shrieve DC, Alexander E III, Kaiser UB, Richardson GE, Black PM, Loeffler JS. Initial clinical results of Linac-based stereotactic radiosurgery and stereotactic radiotherapy for pituitary adenomas. Int J Radiat Oncol Biol Phys 42(3):573-580, 1998.

87. Potts GF, Gugino LD, Leventon ME, Grimson WE, Kikinis R, Cote W, Alexander E III, Anderson JE, Ettinger GJ, Aglio LS, Shenton ME. Visual Hemifield Mapping Using Transcranial Magnetic Stimulation Coregistered With Cortical Surfaces Derived From Magnetic Resonance Images. J Clinical Neurophysiology 15(4): 344-350, 1998.

88. Shrieve DC, Alexander E III, Black PM, Wen PY, Fine HA, Kooy HM, Loeffler JS. Treatment of patients with primary glioblastoma multiforme with standard postoperative radiotherapy and radiosurgical boost: prognostic factors and long-term outcome. J Neurosurg 90:72-77, 1999.

89. Schwartz RB, Hsu L, Wong TZ, Kacher DF, Zamani AA, Black PM, Alexander E III, Stieg PE, Moriarty TM, Martin CA, Kikinis R, Jolesz FA. Intraoperative MR imaging guidance for intracranial neurosurgery: experience with the first 200 cases. Radiology 211(2):477-88, 1999.

90. Alexander E III, Loeffler JS: The case for radiosurgery. Clin Neurosurg 45:32-40, 1999.

91. Black PM, Alexander E III, Martin C, Moriarty T, Nabavi A, Wong TZ, Schwartz RB, Jolesz F. Craniotomy for tumor treatment in an intraoperative magnetic resonance imaging unit. Neurosurgery 45(3): 423-431, 1999.

92. Stieg PE, Friedlander RM, Loeffler JS, Alexander E III: Arteriovenous malformations: Indications for stereotactic radiosurgery. Clin Neurosurg 47:242-248, 2000.

93. Moriarty TM, Quinones-Hinojosa A, Larson PS, Alexander E III, Gleason PL, Schwartz RB, Jolesz FA, Black PM. Frameless stereotactic neurosurgery using intraoperative magnetic resonance imaging: stereotactic brain biopsy. Neurosurgery 47(5): 1138-1146, 2000. (Professional Student Author Larson PS)

94. Rauzzino MJ, Tubbs RS, Alexander E III, Grabb PA, Oakes WJ: Spinal neurenteric cysts and their relation to more common aspects of occult spinal dysraphism. Neurosurg Focus 10 (1): Article 2, 2001.

95. Gugino LD, Aglio LS, Potts G, Grimson WEL, Shenton ME, Kikinis R, Alexander E, Gonzalez AA, Romero R, Ettinger GJ, Cote WA, Leventon ME, Black PM. Perioperative Use of Transcranial Magnetic Stimulation. Techniques in Neurosurgery 7(1): 33-51, 2001.

96. Hodgson DC, Goumnerova LC, Loeffler JS, Dutton S, Black P, Alexander E, Xu R, Silver B, Tarbell NJ. Radiosurgery in the Management of Pediatric Brain Tumors. Int J Radiat Oncol Biol Phys, 50: 929-935, 2001.

97. Villavicencio AT, Black PM, Shrieve DC, Fallon MP, Alexander E, Loeffler JS. Linac Radiosurgery for Skull Base Meningiomas. Acta Neurochirurgica: 143(11);1141-52, 2001.

Learn more about Dr. Alexander’s November 2008 discovery here.

Invited Articles: Original Articles, Review Articles, Book Chapters

1. Alexander, E III, Hildreth, DH. Parachuting and Hang Gliding. In: Sports Injuries: Mechanisms, Prevention and Treatment. Richard C. Schneider, John C. Kennedy, Marcus L. Plant (Eds), Williams & Wilkins, Baltimore 1985: 496- 515.

2. Alexander, E III, Black, P McL. Cerebral blood flow and arteriographic vasospasm: Effects of delayed lavage in an experimental canine model. In: Cerebral Vasospasm. (Wilkins, RH, editor) Raven Press, New York. 1988: 395-401.

3. Nashold, BS, Jr., Alexander, E. Neurosurgical treatment of deafferentation pain. In: Handbook of chronic pain management (Tollison, CD, editor), Williams & Wilkins, Baltimore. 1989:125-135.

4. Eben Alexander Jr. Blaine S. Nashold, Jr. Surg Neurol 36: 1-2, 1991.

5. Loeffler JS, Alexander, E III, Kooy, HM, Wen, PY, Fine, HA, Black, PM: Stereotactic radiosurgery for brain metastases. In: Cancer: Principles and Practice of Oncology, Update, DeVita V, Hellman S, Rosenberg SA (eds) Lippincott, Phildadelphia 1991: 5(2):1-12.

6. Nashold, BS, Jr., Alexander, E III. Neurosurgical relief of pain. In: Textbook of Surgery (Sabiston, DC, editor), W.B. Saunders Co., Philadelphia. 1991: 1275-1281.

7. Rossitch E Jr, Carrazana EJ, Moore MR, Alexander E III, Black PM. El Doctor Harvey Cushing: neurocirujano y illustrador medico. Revista Chilena de Cirugia 1991: 43: 94-96.

8. Alexander E III, Loeffler JS: Radiosurgery using a modified linearaccelerator. In: Neurosurgery Clinics of North America (Lunsford LD, Ed.), W.B. Saunders, Philadelphia, 1992: 3(1): 167-190.

9. Alexander E III, Loeffler JS: Radiosurgery for malignant gliomas. In: Stereotactic Radiosurgery Update (Lunsford LD, Ed.), Elsevier, New York. 1992: 399-406.

10. Loeffler JS, Alexander E III, Wen PY, Fine HA, Kooy HM, Black PM: Radiosurgery for brain metastases: Five year experience at the Brigham & Women's Hospital. In: Stereotactic Radiosurgery Update (Lunsford LD, Ed.), Elsevier, New York. 1992: 383- 392.

11. Loeffler JS, Alexander E III: The role of radiation therapy in the management of astrocytomas. In: Astrocytomas: Diagnosis, Treatment, and Biology. Black P McL, Schoene W, Lampson L (eds), Blackwell, Boston, 1993, pp 73-85.

12. Black P McL, Loeffler JS, Alexander E III, Tarbell NJ, Fine HA, Wen PY, Scott RM, Sallan SE, Moore MR: Cerebral Hemisphere Astrocytomas. In: Astrocytomas: Diagnosis, Treatment, and Biology. Black P McL, Schoene W, Lampson L (eds), Blackwell, Boston, 1993, pp 151-165.

13. Loeffler JS, Tarbell NJ, Dunbar SF, Kooy H, Mannarino E, Bellerive M, Svensson GK, Alexander E III: The potential role of stereotactic radiotherapy in the management of intracranial lesions. Varian 14th Users' Meeting Proceedings, 1992, pp 8-10.

14. Lunsford LD, Alexander E III, Loeffler JS: General Introduction: History of Radiosurgery. In: Stereotactic Radiosurgery. Alexander E III, Loeffler JS, Lunsford LD, (eds), McGraw-Hill, New York, 1993, Chapter 1, pp 1-4.

15. Fontanesi J, Loeffler JS, Alexander E III: Pediatric Tumors. In: Stereotactic Radiosurgery. Alexander E III, Loeffler JS, Lunsford LD, (eds), McGraw-Hill, New York, 1993, Chapter 15, pp 189-196.

16. Loeffler JS, Alexander E III: Radiosurgery for the treatment of intracranial metastases. In: Stereotactic Radiosurgery. Alexander E III, Loeffler JS, Lunsford LD, (eds), McGraw-Hill, New York, 1993, Chapter 16, pp 197-206.

17. Alexander E III, Coffey R, Loeffler JS: Radiosurgery for Gliomas. In: Stereotactic Radiosurgery. Alexander E III, Loeffler JS, Lunsford LD, (eds), McGraw-Hill, New York, 1993, Chapter 17, pp 207-219.

18. Alexander E III, Lindquist C: Special indications: Radiosurgery for functional neurosurgery and epilepsy. In: Stereotactic Radiosurgery. Alexander E III, Loeffler JS, Lunsford LD, (eds), McGraw-Hill, New York, 1993, Chapter 18, pp 221-225.

19. Alexander E III, Leavitt DD, Kooy HM: Future directions: Linear accelerators. In: Stereotactic Radiosurgery. Alexander E III, Loeffler JS, Lunsford LD, (eds), McGraw-Hill, New York, 1993, Chapter 21, pp 243-248.

20. Loeffler JS, Alexander E III, Kooy HM, Black P McL, Tarbell NJ: Stereotactic radiotherapy: rationale, techniques and early results. In: Stereotactic Surgery and Radiosurgery, DeSalles AAF, Goetsch SJ (eds): Medical Physics Publishing, Madison, 1993, pp 307-320.

21. Alexander E III, Black P McL, Wen PY, Fine H, Loeffler JS: Results of radiosurgery versus brachytherapy for malignant gliomas. In: Stereotactic Surgery and Radiosurgery, DeSalles AAF, Goetsch SJ (eds): Medical Physics Publishing, Madison, 1993, pp 455-461.

22. Loeffler, JS, Alexander E III: Radiosurgery in the definitive management of CNS malignancies. In: Organ Conservation in Curative Cancer Treatment, Meyer JL andVaeth JM (eds), Karger, Basel. Frontiers Radiation Therapy and Oncology 27: 227- 244, 1993.

23. Alexander E III, Loeffler JS: Stereotactic radiotherapeutic approaches: Overview. In: Mauch P and Loeffler JS (eds), Radiation Oncology: Technology and Biology, WB Saunders, Philadelphia, 1994, pp 193-197.

24. Alexander E III, Loeffler JS, Kooy HM: Stereotactic Radiosurgery, In: Pell MF and Thomas DGT, (eds), Handbook of Stereotaxy Using the CRW Apparatus: Williams & Wilkins, Baltimore, 1994, pp 179-192.

25. Wen PY, Alexander E III, Loeffler JS: Stereotactic radiosurgery treats intracranial lesions. Diagnostic Imaging. May, 1994, pp 76-107.

26. Loeffler JS, Shrieve DC, Tarbell NJ, Alexander E III: External stereotactic radiation techniques for intracranial lesions. In: Kogelnik HD (ed): Progress in Radio- Oncology V, Monduzzi Editore, Bologna, pp 389-396, 1995.

27. Alexander E III, Loeffler JS: Stereotactic radiosurgical treatment of primary brain tumors, In: Haines SJ, Cohen A (eds): Minimally Invasive Techniques in Neurosurgery, Volume 7, Concepts in Neurosurgery, Williams & Wilkins, Baltimore, 1995, pp. 133- 138.

28. Loeffler JS, Shrieve DC, Wen PY, Fine HA, Kooy HM, Addesa AE, Black PM, Alexander E III: Radiosurgery for intracranial malignancies, In: Schwade J (ed) : Seminars in Radiation Oncology, W.B. Saunders Co., Philadelphia, 5:225-234, 1995.

29. Black PM, Alexander E III, Loeffler JS: New treatments for metastatic brain tumors. In: M Salcman, (ed): Current Techniques in Neurosurgery, 2nd Edition, Current Medicine, Philadelphia, pp. 151-156, 1995.

30. Wen PY, Fine HA, Black PM, Shrieve DC, Alexander E III, Loeffler JS: High-grade astrocytomas. In: Wen PY and Black PM (eds): Brain Tumors in Adults, Neurologic Clinics of North America, W.B. Saunders Co., Philadelphia, 13(4):875-900, 1995.

31. Alexander E III: Skull Base Tumors, In: Samuels MA, Feske S (eds): Office Practice of Neurology, Churchill Livingstone, pp 875-878, 1996.

32. Alexander E III, Loeffler JS: Radiosurgical treatment of intracranial metastases. In: Controversies in Neurosurgery. Al-Mefty O, Origitano TC, Harkey HL (eds), Thieme Medical Publishers, New York, pp. 49-54, 1996.

33. Moriarty TM, Kikinis R, Jolesz FA, Black PM, Alexander E III: Magnetic Resonance Imaging Therapy: Intraoperative MR Imaging, In: Maciunas, RJ (ed): Clinical Frontiers of Interactive Image-Guided Neurosurgery. Neurosurgical Clinics of North America 7(2), W.B. Saunders Co., Philadelphia, pp. 323-331, 1996.

34. Alexander E III, Loeffler JS: Recurrent brain metastases. In: Harsh GR IV (ed). Neurosurgical Clinics of North America, W.B. Saunders, Philadelphia, pp 517-526, 1996.

35. Jolesz FA, Hsu L, Schwartz RB, Zamani AA, Moriarty TM, Alexander E III, Black PM, Wells W, Kikinis R. MRI-guided neuro-interventions. American Society of Neuroradiology, pp 218-219, 1996.

36. Schwartz RB, Moriarty TM, Alexander E III, Black PM, Ainslie MD, Isbister HG, Jolesz FA. Interactive MR-guided intervention of brain lesions. American Society of Neuroradiology, pp 36-37, 1996.

37. Alexander E III, Loeffler JS: Clinical experience with linac radiosurgery, In: Gildenberg P, Tasker R (eds): Stereotactic and Functional Neurosurgery, McGraw-Hill, Inc., New York, pp 745-756, 1997.

38. Nakajima S, Kikinis R, Atsumi H, Leventon M, Hata N, Metcalf D, Moriarty T, Alexander E, Black P, Jolesz F: Image-guided neurosurgery at Brigham and Women's Hospital, In: Tamaki N and Ehara K(ed) Computer-Assisted Neurosurgery, Springer-Verlag Tokyo: 144-162, 1997.

39. Schwartz RB, Hsu L, Black PM, Alexander E III, Stieg PE, Moriarty T, Isbister HG, Cahill CD, Jolesz FA: The value of intraoperative MRI in intercranial procedures, In: Interventional MR: Techniques and clinical experience, FA Jolesz and Ian R Young, Editors. Martin Dunitz Ltd, London, pp. 419-430, 1998.

40. Alexander E III, Kikinis R, Black PM, Jolesz F: Intraoperative Magnetic Resonance Imaging, In: Barnett GH, Maciunas R, Roberts D, (eds): Image-Guided Neurosurgery: Clinical Applications of Interactive Surgical Navigation, Quality Medical Publishers, Inc. St. Louis, MO, pp 215-227, 1998.

41. Moriarty TM, Alexander E III, Stieg PE, Woodard E, Jolesz FA, Black PM. MR guided neurosurgery. Interventional Magnetic Resonance Imaging, eds. Darzi A, Gedroyc W, Gould S. ISIS Medical Press, Oxford, England, 1999.

42. Moriarty TM, Jolesz FA, Alexander E III, Stieg PE, Woodard EJ, Schwartz R, Black PM. Intra-operative MRI for Neurosurgery. Interventional MRI, ed. Lufkin RB, Mosby, Philadelphia, PA. pp. 255-262,1999.

43. Alexander E III, Nashold, BS: A History of Neurosurgical Navigation, In: Alexander E III, Maciunas RJ: Advanced Neurosurgical Navigation, Edited by Alexander E III and Maciunas RJ, Thieme Medical, Stuttgart, New York, 1999, pp. 3-14.

44. Alexander, E III, Garada B, Schwartz RB, Hill JW, Kooy HM: Fusion of Imaging Modalities: Single Photon Emission Computed Tomography, Magnetic Resonance Imaging, Computed Tomography and Angiography, In: Advanced Neurosurgical Navigation, Edited by Alexander E III and Maciunas RJ, Thieme Medical, Stuttgart, New York,. pp. 125-136, 1999.

45. Nakajima S, Kikinis R, Jolesz FA, Atsumi H, Leventon ME, Grimson EL, Hata, N, Metcalf DC, Moriarty TM, Black, PM, Garada B, Alexander E III: Three-Dimensional Magnetic Resonance Imaging Reconstruction for Surgical Planning and Guidance, In: Advanced Neurosurgical Navigation, Edited by Alexander E III and Maciunas RJ, Thieme Medical, Stuttgart, New York, 1999, pp. 137-145.

46. Gugino LD, Potts GF, Aglio LS, Alexander E III, Grimson E, Kikinis R, Shenton ME, Black PM, Ettinger Gil, Cote W, Leventon M, Gonzalez AA: Localization of Eloquent Cortex Using Transcranial Magnetic Stimulation, In: Advanced Neurosurgical Navigation, Edited by Alexander E III and Maciunas RJ, Thieme Medical, Stuttgart, New York, 1999, pp.163-199.

47. Maciunas RJ, Alexander E III, Hill JW: Stereotactic Frame-Based Guidance of Craniotomies: Cosman-Roberts-Wells System, In: Advanced Neurosurgical Navigation, Edited by Alexander E III and Maciunas RJ, Thieme Medical, Stuttgart, New York, 1999, pp. 289-300.

48. Alexander E III, Hill JW, Loeffler JS: Radiosurgery for Malignant Brain Tumors, In Advanced Neurosurgical Navigation, Edited by Alexander E III and Maciunas RJ, Thieme Medical, Stuttgart, New York,, pp. 427-441, 1999.

49. Alexander E III, Black PM, Martin CH, Kikinis R, Hill JW, Jolesz FA: Intraoperative Magnetic Resonance Imaging, In: Advanced Neurosurgical Navigation, Edited by Alexander E III and Maciunas RJ, Thieme Medical, Stuttgart, New York,, pp. 530- 538, 1999.

50. Maciunas RJ, Alexander E III: Future Advances in Neurosurgical Navigation, In: Advanced Neurosurgical Navigation, Edited by Alexander E III and Maciunas RJ, Thieme Medical, Stuttgart, New York, pp. 585-588, 1999.

51. Alexander E III, Loeffler JS: The role of radiosurgery for glial neoplasms. Neurosurg Clin N Am: 10(2):351-8, 1999.

52. Black PM, Martin CH, Alexander E III, Moriarty T, Stieg PA, Woodard E, Schwartz R, Wong T, Jolesz F. Imaging of the nervous system during surgery: General considerations and limitations. In: Neurosurgery: The scientific basis of clinical practice (Edition 3), (Chapter Number 58), Edited by Crockard A, Hayward R and Hoff JT, (Vol 2) Blackwell Science, Oxford, pp. 867-876, 2000.

53. Martin C, Alexander E III, Jolesz F, Black PM. Surgery in the MRI environment, In: Operative Neurosurgery, Edited by Andrew H. Kaye and Peter McL. Black, Churchill-Livingstone, London, pp. 185-198, 2000.

54. Alexander E III, Loeffler JS. Radiosurgery for metastases, In: Operative Neurosurgery, Edited by Andrew H. Kaye and Peter McL. Black, Churchill-Livingstone, London, pp. 407-416, 2000.

55. Alexander E III. Optimizing brain tumor resection: Midfield interventional MR imaging. In: MR-Guided Therapy in Neurosurgery,: Edited by Truwit C. Neuroimaging Clin N Am: 11 (4): 659-672, 2001.

56. Stieg PE, Friedlander RM. Loeffler JS, Alexander E III. Arteriovenous malformations: indications for stereotactic radiosurgery. Clinical Neurosurgery. 36 (47) 242-248, 2001.

57. Alexander E III. Linac Radiosurgery, In: Youmans Neurological Surgery, Edited by HR Winn, Saunders-Elsevier, Philadelphia, pp. 4111-4116, 2004.

Learn more about Dr. Alexander’s November 2008 discovery here.

Books And Supplements

1. Alexander E III, Loeffler JS, Gildenberg PL, Franklin PO (Eds): Radiosurgery: Enhancement of Clinical Excellence. In: Stereotactic and Functional Neurosurgery: 57(1): 112 pp, 1992.

2. Alexander E III, Loeffler JS, Lunsford LD (Eds): StereotacticRadiosurgery. McGraw-Hill, New York, 272 pp., 1993.

3. Alexander E III, Kondziolka D, Lindquist C, Loeffler JS: Radiosurgery 1995, Karger, Basel, 350 pp, 1996.

4. Alexander E III, Kondziolka D, Lindquist C, Loeffler JS: Radiosurgery 1997, Karger, Basel, 268 pp, 1998.

5. Alexander E III, Maciunas RJ: Advanced Neurosurgical Navigation,Thieme Medical, Stuttgart, New York, 605 pp, 1999.

6. Alexander E III, Kondziolka D, Lindquist C, Loeffler JS, Smee R:Radiosurgery 1999, Karger, Basel, 293 pp, 2000.

Letters

1. Alexander, E III: Mild to Moderate head injury, Eds JT Hoff, TE Anderson, TM Cole. Boston, Blackwell Scientific, 1989 (Book review). New Eng. J. Med. pp 282 7/26/1990

2. Loeffler, JS, Alexander, E III, Larson, D: Stereotactic radiation for intracranial arteriovenous malformations (letter). N Engl J Med, 1990: 323(23): 1636.

3. Loeffler JS, Alexander E III: Critique of stereotactic radiosurgery for intracranial arteriovenous malformations using a standard linear accelerator. Int J Radiat Oncol Biol Phys 18:1536,1990.

4. Alexander E III, Loeffler JS: Comment: Stereotactic radiosurgery of angiographically occult vascular malformations: Indications and preliminary experience. Neurosurgery 27: 900, 1990.

5. Loeffler JS, Alexander E III, Fine HA, Wen PY, Kooy HM, Black P McL,Shea WM: Use of radiosurgery in the treatment of malignant glioma. J Clin Oncol 2:195, 1993.

6. Alexander E III, Mulkern RV, Loeffler JS: Accuracy of stereotaxis. J Neurosurgery 84:303-304, 1996 Source

Learn more about Dr. Alexander’s November 2008 discovery here.